Primary yolk sac tumor of the urachus.

Autor: Romero-Rojas AE; Grupo de Patología del Instituto Nacional de Cancerología INC, Bogotá, Colombia. aromero@cancer.gov.co, Messa-Botero OA, Melo-Uribe MA, Díaz-Pérez JA, Chinchilla-Olaya SI
Jazyk: angličtina
Zdroj: International journal of surgical pathology [Int J Surg Pathol] 2011 Oct; Vol. 19 (5), pp. 658-61. Date of Electronic Publication: 2009 Dec 24.
DOI: 10.1177/1066896909356923
Abstrakt: Introduction: Neoplasms originating from the urachus are rare. The most common urachal malignancy is adenocarcinoma, whereas extragonadal germ cell tumors, primarily of the urachus, are an extremely rare finding.
Objective: To describe a primary yolk sac tumor (YST) of the urachus in an adult.
Case Report: A 44-year-old woman presented with 6 months of pelvic pain associated with a sensation of progressive mass growth. At the time of tumor resection, the tumor was found to be attached by a pedicle to the dome of the bladder, with no injury to the adjacent organs. Pathological study showed a neoplasm with epithelioid cells, pseudocysts, a myxomatous background, and Schiller-Duval body formations. Immunohistochemistry stains showed positivity to AE1/AE3, α-1-fetoprotein, and α-1-antitrypsin and negativity to other markers.
Conclusion: An unusual case of a YST in the urachus is presented. This is the first reported adult case based on the authors' bibliographic search.
Databáze: MEDLINE