Recent development of acupuncture on Parkinson's disease.
| Autor: | Joh TH; Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY 10021, USA., Park HJ, Kim SN, Lee H |
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| Jazyk: | angličtina |
| Zdroj: | Neurological research [Neurol Res] 2010 Feb; Vol. 32 Suppl 1, pp. 5-9. |
| DOI: | 10.1179/016164109X12537002793643 |
| Abstrakt: | Objectives: Parkinson's disease is a complex disease with multiple etiological factors involved in disease pathogenesis, and the molecular and cellular pathways for neurodegeneration are still elusive. Methods: We reviewed all the relevant laboratory findings regarding acupuncture mechanism on Parkinson's disease. Results: Acupuncture treatments in animal experiments have generated valuable mechanistic insights of Parkinson's disease and shown that acupuncture therapy is in fact a neuroprotective therapy which increases various neuroprotective agents such as brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and cyclophilin A. In addition, acupuncture therapy decreases cell death processes and attenuates oxidative stress to substantia nigra dopaminergic neurons. Discussion: These results suggest that early application of acupuncture therapy for Parkinson's disease patients may be helpful for the best efficacy of acupuncture treatment. |
| Databáze: | MEDLINE |
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