| Autor: |
Peng L; Department of Bioengineering and Therapeutic Sciences, Department of Physiology, University of California-San Francisco, San Francisco, CA 94158-2330, USA., Barczak AJ, Barbeau RA, Xiao Y, LaTempa TJ, Grimes CA, Desai TA |
| Jazyk: |
angličtina |
| Zdroj: |
Nano letters [Nano Lett] 2010 Jan; Vol. 10 (1), pp. 143-8. |
| DOI: |
10.1021/nl903043z |
| Abstrakt: |
The response of primary human endothelial (ECs) and vascular smooth muscle cells (VSMCs) to TiO2 nanotube arrays is studied through gene expression analysis. Microarrays revealed that nanotubes enhanced EC proliferation and motility, decreased VSMC proliferation, and decreased expression of molecules involved in inflammation and coagulation in both cell types. Networks generated from significantly affected genes suggest that cells may be sensing nanotopographical cues via pathways previously implicated in sensing shear stress. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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