[Relapse after surgical treatment of mycobacterium ulcerans infection (buruli ulcer): study of risk factors in 84 patients in the Democratic Republic of the Congo].

Autor:	Kibadi K; Département de Chirurgie, Faculté de Médecine, Université de Kinshasa, République Démocratique du Congo. akibadi@yahoo.fr, Mputu-Yamba JB, Mokassa B, Panda M, Muyembe-Tamfum JJ
Jazyk:	francouzština
Zdroj:	Medecine tropicale : revue du Corps de sante colonial [Med Trop (Mars)] 2009 Oct; Vol. 69 (5), pp. 471-4.
Abstrakt:	Objective: To identify risk factors for relapse after exclusively surgical treatment of Mycobacterium ulcerans infection (Buruli ulcer). Methods: Study was carried out in 102 patients treated exclusively by surgery for Buruli ulcer at various care facilities in the Congo from January 1, 2000 to January 1, 2005. Results: Outcomes included relapse in 22 patients (21.5%), cure in 62 (60.7%), and unknown in 18 (17.6%). Statistical analysis identified the following variables as independent risk factors for relapse after exclusively surgical treatment: incomplete surgical excision (OR = 91.83; P = 0.0000; IC to 95%), age under 16 years (OR = 14.80; P = 0.0000; IC to 95%) and pre-ulcerative Buruli lesions (edema and plaque) (OR = 3.18; P = 0.0215; IC to 95%). Conclusion: Quality of excision, patient age, and clinical form of lesion are the main predictors of relapse after isolated surgical treatment of Buruli ulcer.
Databáze:	MEDLINE
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