[Influence of immunological parameters on the effectiveness of systemic and loco-regional immunotherapy in disseminated renal carcinoma].

Autor: Granov AM, Molchanov OE, Karelin MI, Shkol'nik MI, Krotova OA
Jazyk: ruština
Zdroj: Voprosy onkologii [Vopr Onkol] 2009; Vol. 55 (5), pp. 580-5.
Abstrakt: Survival was assessed among patients with disseminated renal carcinoma from different prognostic groups as established by MSKCC protocol. Multivariate evaluation pointed to prognostic value of IL-6 (spontaneous and induced production), IL-8 (spontaneous and induced production),TNF-alpha (spontaneous production), IFN-gamma (induced production), TNK-cells (CD3+CD16+CD56+), and T-regulatory cells (CD4+CD25+Treg). It was demonstrated that additional criteria may be used to evaluate prognosis.
Databáze: MEDLINE