| Autor: |
Larrivée-Aboussafy C; Development Science and Technology, Pfizer Inc., Eastern Point Road, Groton, Connecticut 06340, USA., Jones BP, Price KE, Hardink MA, McLaughlin RW, Lillie BM, Hawkins JM, Vaidyanathan R |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2010 Jan 15; Vol. 12 (2), pp. 324-7. |
| DOI: |
10.1021/ol9026599 |
| Abstrakt: |
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been found to catalyze the amidation of acyl imidazoles. The rate acceleration is especially evident with traditionally unreactive, electron-deficient anilines. DBU is readily available and offers safety and cost advantages over more commonly employed catalysts such as 1-hydroxybenzotriazole. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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