Neuropsychological assessment of current and past crack cocaine users.

Autor: De Oliveira LG; Department of Psychiatry, Medical School, Universidade de São Paulo (USP), São Paulo (SP), Brazil. luciogoliver@usp.br [corrected], Barroso LP, Silveira CM, Sanchez ZV, De Carvalho Ponce J, Vaz LJ, Nappo SA
Jazyk: angličtina
Zdroj: Substance use & misuse [Subst Use Misuse] 2009; Vol. 44 (13), pp. 1941-57.
DOI: 10.3109/10826080902848897
Abstrakt: Background: Cognitive changes due to crack cocaine consumption remain unclear.
Methods: For clarification, 55 subjects were assigned to three groups: control group, crack cocaine current users, and ex-users. Participants were submitted to Mini-Mental State Examination (MMSE) and tasks evaluating executive functioning and verbal memory. Mood state was also measured. Intergroup comparisons were carried out.
Results: Control group performance on the MMSE was better than that of users and ex-users. Verbal memory performance for logical memory of users was impaired. Ex-users scored lower on DSST and Trail Making Test (Part B).
Conclusion: Chronic crack cocaine use seems to disrupt general cognitive functioning (MMSE), verbal memory, and attentional resources, but findings suggest that some of these effects could be reversed by abstinence.
Databáze: MEDLINE
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