[Pathogenesis of infectious conjunctivitis in Nepal].

Autor:	Naito T; Department of Ophthalmology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan. naito@clin.med.tokushima-u.ac.jp, Aoki K, Ohguchi T, Ohgami K, Ohno S, Shiot H, Shrestha JK, Upadhyay MP
Jazyk:	japonština
Zdroj:	Nippon Ganka Gakkai zasshi [Nippon Ganka Gakkai Zasshi] 2009 Nov; Vol. 113 (11), pp. 1088-91.
Abstrakt:	Purpose: We investigated human adenovirus (HAdV) and Chlamydia trachomatis in patients with infectious conjunctivitis in Nepal. Method: We obtained swabs from 6 patients with infectious conjunctivitis in a remote area near the Indian border (group A), and from 30 patients at the B. P. Koirala Eye Center of Tribhuvan University Teaching Hospital in Kathmandu (group B). Rapid diagnosis of HAdV was conducted in Nepal, using Capilia adeno eye (Capilia), a rapid adenoviral antigen diagnostic kit using immunochromatography. Residual swabs were brought to Japan and examined for HAdV and Chlamydia trachomatis using polymerase chain reaction (PCR). Etiological analysis of 214 patients with trachoma was also investigated by PCR. Results: Capilia results were negative for the six samples of group A and positive for 13 patients (43%) in group B. PCR showed one (17%) as positive in group A and 30 (100%)in group B. The serotype of all HAdV positive samples was HAdV-8. C serovar of Chlamydia trachomatis was detected in ninety seven cases out of 214 patients with trachoma. Conclusion: HAdV-8 and Chlamydia trachomatis serotype C seem to be prevalent in Nepal.
Databáze:	MEDLINE
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