| Autor: |
Pakharukova NA, Nosovskiĭ AM, Pastushkova LKh, Trifonova OP, Larina IM |
| Jazyk: |
ruština |
| Zdroj: |
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine [Aviakosm Ekolog Med] 2009 Jul-Aug; Vol. 43 (4), pp. 60-6. |
| Abstrakt: |
Variability analysis of normal human proteoma requires a valid and crisp algorithm for mass-spectrometry data analysis. The goal was to test methods of statistical analysis of blood serum proteoma profiles in an experiment with 24-hr. HDT using the small sample nonparametric criteria. The investigation revealed peaks that appear to be a molecular response of organism to simulated microgravity. Further identification of fiducially mobile peaks with the help of tandem mass-spectrometry will enable disclosure of subtle mechanisms of adaptation to the spaceflight factors and improvement of human health evaluation in space missions of varying length. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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