[Osteointegration of an alumina matrix composite ceramic with a porous surface: mechanical and histological results of an animal experiment].
| Autor: | Schreiner U; Orthopädisch-Unfallchirurgisches Zentrum, Universitätsklinik Mannheim. ute.schreiner@ortho.ma.uniheidelberg.de, Koester H, Pott P, Scheller G, Schwarz M |
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| Jazyk: | němčina |
| Zdroj: | Zeitschrift fur Orthopadie und Unfallchirurgie [Z Orthop Unfall] 2009 Sep-Oct; Vol. 147 (5), pp. 603-9. |
| DOI: | 10.1055/s-0029-1185623 |
| Abstrakt: | Introduction: The aim of this study was to analyse mechanically and histologically the osteointegration of porous-surfaced ceramic implants made of an alumina matrix composite (AMC) by assessing maximum shear strength and histomorphometric bone ongrowth. Methods: The surfaces of the cylindrically shaped AMC test implants were characterised by a porosity of 40% and a pore size of 150 to 300 microm. A total of 24 test cylinders was implanted bilaterally into the femurs of 6 female adult Goettinger minipigs. 12 weeks after surgery the animals were sacrificed. 12 test implants were used for a push-out test and 12 test implants were evaluated histologically. Results: The mean maximum shear strength of the bone-implant interface was 7.6 +/- 2.0 MPa. Direct bone attachment was found in 7.4 +/- 3.4% of the histologically analysed surfaces. Conclusion: In summary, porous-surfaced AMC test implants demonstrated good mechanical stability in spite of a low percentage of bone ongrowth. This discrepancy could potentially be explained by bone ingrowth into the pores and subsequent interlocking mechanisms. |
| Databáze: | MEDLINE |
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