Frequency of left ventricular diastolic dysfunction by mitral doppler in healthy elderly individuals.

Autor:	Alves-Silva LS; Hospital Universitário Prof. Edgard Santos, Universidade Federal da Bahia, Salvador, BA, Brasil. lsergio@cardiol.br, Câmara EJ, Souza CA
Jazyk:	English; Portuguese; Spanish; Castilian
Zdroj:	Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2009 Oct; Vol. 93 (4), pp. 328-33, 321-6.
DOI:	10.1590/s0066-782x2009001000004
Abstrakt:	Background: Healthy elderly individuals present alterations in mitral Doppler velocities, which are characteristic of left ventricular (LV) diastolic dysfunction with impaired relaxation. Objective: To determine the frequency of LV diastolic dysfunction by mitral Doppler in healthy elderly individuals and identify clinical and echocardiographic characteristics associated to this finding. Methods: Seventy-three apparently healthy individuals (64% women, aged 60 to 80) were carefully selected and submitted to clinical, laboratory and Doppler-echocardiographic assessment, with particular regard to the characteristics of the mitral flow. Results: A total of 33 patients (45%) presented an impaired LV relaxation pattern (group I), characterized by the association between the maximum velocities of the mitral wave flow (E/A ratio) <0.75 or E-wave deceleration time >240 ms, and 40 (55%) with a normal pattern (group II). Group I presented a larger aortic root diameter (32.1 + or - 4.2 vs 30.3 + or - 3.3 mm; p = 0.044) and a longer PR interval (156 + or - 22 vs 139 + or - 23 ms; p = 0.002). Conclusion: A large proportion of individuals aged 60 to 80 years present normal diastolic function at the Doppler-echocardiographic assessment of the mitral flow. Healthy elderly individuals with impaired LV relaxation filling have a larger aortic root diameter and longer PR interval.
Databáze:	MEDLINE
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