| Autor: |
Shi Y; Department of Chemistry, University of California, Irvine, California 92697-2025, USA., Roth KE, Ramgren SD, Blum SA |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Chemical Society [J Am Chem Soc] 2009 Dec 23; Vol. 131 (50), pp. 18022-3. |
| DOI: |
10.1021/ja9068497 |
| Abstrakt: |
A new strategy for gold and palladium dual-catalytic reactivity and turnover, called catalyzed catalysis, enhanced the synthetic usefulness of vinylgold intermediates by providing dual-catalytic carbon-carbon cross-coupling as an alternative to protodemetalation. This protocol enabled the synthesis of substituted butenolides and isocoumarins from allyl esters. Kinetic and spectroscopic experiments support a mechanism in which the Lewis acidic gold complex catalyzes both an initial rearrangement step and a subsequent Lewis basic palladium oxidative-addition step. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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