[Splenectomy in hereditary hemolytic anemia: 82 Tunisian cases].

Autor:	Hafsia R; Service d'Hématologie biologique Hôpital Aziza Othmana, Tunis., Zriba S, Gouider E, Ben Salah N, Borji W, Zaouche A
Jazyk:	francouzština
Zdroj:	La Tunisie medicale [Tunis Med] 2009 May; Vol. 87 (5), pp. 323-7.
Abstrakt:	Background: Splenectomy is frequently advised in hereditary hemolytic anemia. Severe complications could occur after splenectomy. Aim: To provide the indication and benefit of splenectomy Methods: clinical and biological patterns were performed in a retrospective study of 82 patients: 17 homozygous beta thalassemia, 17 thalassemia intermedia, 33 heterozygote Hb/S beta thalassemia and 15 hereditary spherocytosis. Results: Splenectomy was performed for: Hypertransfusion in homozygous thalassemia, hereditary spherocytosis; hypersplenism in Thalassemia intermedia and splenic sequestration in heterozygote HbS/beta thalassemia. The benefit of splenectomy was proved in hereditary spherocytosis (100%), heterozygote HbS/beta thalassemia (90%) and thalassemia intermedia (75%); nevertheless in homozygous beta thalassemia. Post splenectomical complication are often thrombocytosis, thrombosis and infections. Conclusion: Splenectomy should be performed in hereditary hemolytic anemia to reduce and avoid transfusion.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu