[Vanishing prostate cancer. Clinical presentation and histological review].

Autor: Ebel Sepúlveda L; Servicio de Urología, Hospital Base Valdivia, Valdivia, Chile. luisebel@uach.cl, Corti D, Foneron A, Troncoso L, Gil G, Carpio D, Cañoles R, Hornig A, Valdevenito G
Jazyk: Spanish; Castilian
Zdroj: Actas urologicas espanolas [Actas Urol Esp] 2009 Oct; Vol. 33 (9), pp. 956-9.
DOI: 10.1016/s0210-4806(09)72893-1
Abstrakt: The impossibility to identify cancer in the final surgical specimen has been reported in some patients with prostate cancer undergoing radical prostatectomy. This has been attributed to either a wrong diagnosis or pathological technique, or to spontaneous or biopsy-induced cure of the tumor. This study assessed the incidence of vanishing prostate cancer in our department for 12 years, the clinical characteristics of patients, and their follow-up. The initial puncture biopsies were also re-evaluated using inmunohistochemical stains. Prostate cancer could not be confirmed in the surgical specimen in six out of 346 operated patients (1.73%) receiving no neoadjuvant therapy. When the initial biopsies were reviewed, cancer was only confirmed in three patients. Incidence of vanishing cancer at our department in the 12-year period considered was 0.86% (3/346). No tumor relapse occurred during 4.5 years of follow-up.
(Copyright 2009 AEU. Published by Elsevier España, S.L. All rights reserved.)
Databáze: MEDLINE