| Autor: |
Baĭder LM, Reutov VP, Krushinskiĭ AL, Kuzenkov VS, Sorokina EG, Koshelev VB, Fadiukov OE, Zhymabaeva TT, Lozinova TA, Komissarova LKh, Pinelis VG, Kositsin NS, Kuropteva ZV |
| Jazyk: |
ruština |
| Zdroj: |
Biofizika [Biofizika] 2009 Sep-Oct; Vol. 54 (5), pp. 894-900. |
| Abstrakt: |
The influence of hypoxia on nitric oxide formation in the blood of Krushinskii-Molodkina rats has been studied by electron paramagnetic resonance. It was found that nitric oxide synthesis in Krushinskii-Molodkina rats is increased compared with that in Wistar rats. A significant enhancement of the EPR signal of Hb-NO complexes in the animal blood was observed after hypoxia simulating the altitude of 5000 m above the sea level, in particular in the presence of sodium nitrite and the NO-synthase inhibitor L-nitroarginine. It was assumed that NO synthesis and nitro-/nitrite- reductase systems are activated under hypoxic conditions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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