[Role of hydrogen ions in the regulation of the redox state of erythrocytes].

Autor: Martinovich GG, Martinovich IV, Golubeva EN, Cherenkevich SN
Jazyk: ruština
Zdroj: Biofizika [Biofizika] 2009 Sep-Oct; Vol. 54 (5), pp. 846-51.
Abstrakt: The parameters of the acid-base state and redox state of erythrocytes have been studied with the use of the fluorescent probes 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein and 2',7'-dichlorodihydrofluorescein. It has been found that the value of redox state parameters in erythrocytes depends both on the extracellular and intracellular concentrations of hydrogen ions. It has been shown that hydrogen peroxide induces a decrease in the value of the intracellular pH. The interrelation of cellular homeostasis parameters characterizing the acid-base and redox states of erythrocytes has been theoretically and experimentally substantiated.
Databáze: MEDLINE