[Prevention of adhesions in abdominal surgery. A dose finding study with streptokinase/streptodornase].

Autor: Tuchmann A; I. Chirurgische Abteilung KA Rudolfstiftung Wien., Dinstl K, Depisch D, Wendt P, Blümel G
Jazyk: němčina
Zdroj: Langenbecks Archiv fur Chirurgie. Supplement II, Verhandlungen der Deutschen Gesellschaft fur Chirurgie. Deutsche Gesellschaft fur Chirurgie. Kongress [Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir] 1990, pp. 1041-5.
Abstrakt: Unlabelled: Measurement of intraperitoneal fibrinolytic activity on 50 patients having undergone abdominal surgery (four of them controls). Instillation of streptokinase/streptodornase (Varidase) into the abdominal cavity. Determination of total protein, plasminogen, antiplasmin, alpha 2 Mx-plasmin-complex, spontaneous fibrinolysis and fibrinolysis + activator at different points in time p.op.
Results: Intraperitoneal fibrinolysis may be stimulated by local substitution of a plasminogen activator (Varidase). Systemic effects are confined to a high dose. No impaired wound healing nor increased propensity to hemorrhaging occurred.
Databáze: MEDLINE