| Autor: |
de Freitas JA; Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, GO, Brazil., Prudente MF, Carvalhaes MS |
| Jazyk: |
angličtina |
| Zdroj: |
Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2009 Jul-Aug; Vol. 42 (4), pp. 381-5. |
| DOI: |
10.1590/s0037-86822009000400005 |
| Abstrakt: |
Lagochilascaris minor is the etiological agent of lagochilascariosis, a disease that affects the neck region and causes exudative abscesses, with eggs, adult parasites and L3/L4 larvae in the purulent exudates. Mice are now considered to be intermediate hosts for the parasite. To determine the pattern of infection in B1 cell-deficient mice, experimental lagochilascariosis was studied in BALB/c and X-chromosome-linked immunodeficient (xid) mice. BALB.xid-infected mice showed lower numbers of larvae. Third-stage larvae, fourth-stage larvae and adult parasites were found in both strains. BALB/c mice produced IgM, IgG, IgA and IgE against the crude extract and secreted/excreted antigens of the parasite. On the other hand, BALB.xid mice did not produce IgM and produced lower levels of IgG and IgA, and similar quantities of IgE. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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