| Autor: |
Puzdrova VA; Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia. puzdrova@mail.ru, Kargina-Terent'eva RA, Tarasova OS |
| Jazyk: |
angličtina |
| Zdroj: |
Neuroscience and behavioral physiology [Neurosci Behav Physiol] 2009 Oct; Vol. 39 (8), pp. 757-61. Date of Electronic Publication: 2009 Sep 23. |
| DOI: |
10.1007/s11055-009-9194-7 |
| Abstrakt: |
The effects of chronic hypotension on the density and intensity of fluorescence (after treatment with glyoxylic acid) of the plexus of adrenergic fibers in the wall of the saphenous artery and on the reinnervation of this vessel were studied in Wistar rats. Regional hypotension in the vascular bed of the hind part of the rats' bodies was induced by stenosis of the abdominal part of the aorta distal to the renal arteries. After four weeks, the saphenous artery was denervated in one limb by resection of a segment of the femoral nerve. In the limb with the nerve lesion, chronic (6-7 weeks) hypotension led to a reduction in the intensity of nerve fiber fluorescence by 20% as compared with normotensive animals (controls), though the density of the nerve plexus did not change. Partial reinnervation of the vessel was observed 2-3 weeks after femoral nerve lesioning. Measures of reinnervation in normotensive and hypotensive rats were no different at two weeks, though at three weeks rats with hypotension showed more complete recovery of innervation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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