Clinical and molecular epidemiology of methicillin-resistant Staphylococcus aureus carrying SCCmecIV in a university hospital in Porto Alegre, Brazil.

Autor: Scribel LV; Medical Sciences Post-graduate Program, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Silva-Carvalho MC, Souza RR, Superti SV, Kvitko CH, Figueiredo AM, Zavascki AP
Jazyk: angličtina
Zdroj: Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2009 Dec; Vol. 65 (4), pp. 457-61. Date of Electronic Publication: 2009 Sep 19.
DOI: 10.1016/j.diagmicrobio.2009.08.012
Abstrakt: We evaluated clinical outcomes and molecular epidemiology of methicillin-resistant Staphylococcus aureus carrying SCCmecIV recovered from patients who attended at a teaching hospital from Porto Alegre, Brazil. All Panton-Valentine leukocidin (PVL)-producer isolates belonged to clonal complex (CC) 30 (11 isolates, related to Oceania Southwest Pacific clone [OSPC]), and the PVL-negative isolates were typed as CC5 (2 isolates, related to the pediatric clone). Five patients had health care-associated infections (HCAIs) with hospital-onset, 5 HCAIs with community-onset, and 3 community-acquired infections without risks. A high overall mortality (30.8%) was found. This study show that OSPC isolates are not only causing community-associated infections but are also involved in HCAI in our country.
Databáze: MEDLINE