A comparison of intravenous oxycodone and intravenous morphine in patient-controlled postoperative analgesia after laparoscopic hysterectomy.
| Autor: | Lenz H; University of Oslo, Faculty Division Ullevaal University Hospital, Oslo, Norway. harald.lenz@medisin.uio.no, Sandvik L, Qvigstad E, Bjerkelund CE, Raeder J |
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| Jazyk: | angličtina |
| Zdroj: | Anesthesia and analgesia [Anesth Analg] 2009 Oct; Vol. 109 (4), pp. 1279-83. |
| DOI: | 10.1213/ane.0b013e3181b0f0bb |
| Abstrakt: | Introduction: In this study, we investigated the dose requirements, pain relief, and side effects of oxycodone versus morphine after surgery with visceral pain. Methods: Ninety-one women received IV oxycodone or morphine before the end of laparoscopic hysterectomy and then continued with patient-controlled analgesia for 24 h postoperatively. Results: The accumulated oxycodone consumption was less (13.3 +/- 10.4 mg vs 22.0 +/- 13.1 mg, P = 0.001) than morphine. With oxycodone, the visual analog scale scores were significantly lower in the first hour postoperatively and sedation was less during the 24-h postoperative period, P = 0.006. Conclusions: Oxycodone was more potent than morphine for visceral pain relief but not for sedation. |
| Databáze: | MEDLINE |
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