Platypnea-orthodeoxia syndrome: a diagnostic challenge.

Autor: Desouza KA; Department of Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA. Desouza@seas.wustl.edu, Saraswat S, DeSouza SA, Rajaram V, Reddy PC, Mosley L, Tandon N
Jazyk: angličtina
Zdroj: Southern medical journal [South Med J] 2009 Oct; Vol. 102 (10), pp. 1046-8.
DOI: 10.1097/SMJ.0b013e3181b35f0f
Abstrakt: Platypnea-orthodeoxia (P-O) syndrome is an underdiagnosed condition characterized by dyspnea and deoxygenation accompanying a change from a recumbent to an upright position. It is caused by increased right-to-left shunting of blood on assuming an upright position. The diagnosis of this shunt is often challenging. A case where a diagnosis was missed despite performing a tilt transesophageal echocardiogram with bubble study and a technetium labeled macroaggregated albumin scan is presented. However, a large patent foramen ovale (PFO) was found on autopsy. A brief overview of the diagnostic workup and management of this condition along with methods to increase the sensitivity of diagnostic tests is discussed.
Databáze: MEDLINE