The circulation of human astrovirus genotypes in the Central West Region of Brazil.

Autor: Silva PA; Laboratório de Virologia, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Setor Universitário, 74605-050 Goiânia, Brasil., Santos RA, Costa PS, Teixeira JM, Giugliano LG, Andreasi MS, Leite JP, Schreier E, Cardoso Dd
Jazyk: angličtina
Zdroj: Memorias do Instituto Oswaldo Cruz [Mem Inst Oswaldo Cruz] 2009 Jul; Vol. 104 (4), pp. 655-8.
DOI: 10.1590/s0074-02762009000400021
Abstrakt: Out of 1,588 faecal samples of children taken from three locations of the Central West Region of Brazil, 57 were positive for astroviruses (HAstVs) using reverse transcription-polymerase chain reaction (RT-PCR). They were genotyped by nested RT-PCR and/or genomic sequencing. HAstV-1 (42.8%), HAstV-2 (23.2%), HAstV-3 (3.6%), HAstV-4 (14.3%) and HAstVs -5, -6, -7 and -8 (1.8% each) were detected. In Goiânia and Campo Grande, HAstV-1 was the most frequently detected genotype while in Brasília (DF) it was HAstV-2. Shifts in the circulation of astrovirus genotypes were observed in DF and Campo Grande. All samples collected by rectal swabs were viral negative. The astrovirus genotypes were detected in all age groups and there was no correlation between genotype and age group.
Databáze: MEDLINE