Angiosarcoma of skull base in a 1-year-old child--a case report.

Autor: Renukaswamy GM; Otolaryngology Department, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom., Boardman SJ, Sebire NJ, Hartley BE
Jazyk: angličtina
Zdroj: International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2009 Nov; Vol. 73 (11), pp. 1598-600. Date of Electronic Publication: 2009 Aug 27.
DOI: 10.1016/j.ijporl.2009.07.025
Abstrakt: Angiosarcoma is a rare tumour of endothelial cell origin whilst malignant skull base tumours are highly unusual in paediatric patients. This case reports an angiosarcoma involving the clivus and basi-sphenoid region of the skull base, in a 1-year-old boy. This tumour is extremely rare in childhood, particularly in this site. The histological features were consistent with a high-grade haemangioendothelioma, categorised as an angiosarcoma. The characteristics of this rare malignancy and the challenges in its management are discussed. This is the youngest reported patient, to our knowledge, with an angiosarcoma of the skull base.
Databáze: MEDLINE