| Autor: |
Bautista CT; US Military HIV Research Program, Division of Retrovirology, Walter Reed Army Institute of Research (WRAIR), Suite 250, Rockville, MD 20850, USA. cbautista@hivresearch.org, Singer DE, O'Connell RJ, Crum-Cianflone N, Agan BK, Malia JA, Sanchez JL, Peel SA, Michael NL, Scott PT |
| Jazyk: |
angličtina |
| Zdroj: |
International journal of STD & AIDS [Int J STD AIDS] 2009 Sep; Vol. 20 (9), pp. 634-7. |
| DOI: |
10.1258/ijsa.2008.008413 |
| Abstrakt: |
US military personnel are routinely screened for HIV infection. Herpes simplex virus type 2 (HSV-2) is a risk factor for HIV acquisition. To determine the association between HSV-2 and HIV, a matched case-control study was conducted among US Army and Air Force service members with incident HIV infections (cases) randomly matched with two HIV-uninfected service members (controls) between 2000 and 2004. HSV-2 prevalence was significantly higher among cases (30.3%, 138/456) than among controls (9.7%, 88/912, P < 0.001). HSV-2 was strongly associated with HIV in univariate (odds ratio [OR] = 4.2, 95% confidence interval [CI] = 3.1-5.8) and multiple analyses (adjusted [OR] = 3.9, 95% CI = 2.8-5.6). The population attributable risk percentage of HIV infection due to HSV-2 was 23%. Identifying HSV-2 infections may afford the opportunity to provide targeted behavioural interventions that could decrease the incidence of HIV infections in the US military population; further studies are needed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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