High prevalence of antimicrobial drug-resistant diarrheagenic Escherichia coli in asymptomatic children living in an urban slum.

Autor: Souza TB; Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, 04023-062, São Paulo, Brazil., Morais MB, Tahan S, Melli LC, Rodrigues MS, Scaletsky IC
Jazyk: angličtina
Zdroj: The Journal of infection [J Infect] 2009 Oct; Vol. 59 (4), pp. 247-51. Date of Electronic Publication: 2009 Aug 23.
DOI: 10.1016/j.jinf.2009.08.007
Abstrakt: Purpose: The aim of this study was to investigate the presence of diarrheagenic Escherichia coli and antibiotic resistance in asymptomatic school-age children living in an area with defective environmental sanitation, comparing with children registered at a private school, both in the city of Osasco, Brazil.
Methods: Seventy-nine school-age children between 5 and 10 years living in a slum and 35 children who attended a private school of the same city were included in the study.
Results: DEC was found in 58% of the children living in the slum and in 17% of the control group (P=0.001). Resistance to at least one antimicrobial drug was found in 65% of DEC strains; resistant to two or more antimicrobial drugs was found in 46% of strains.
Conclusion: The high carriage status among the slum children point towards the widespread environment contamination in low socio-economic housing conditions, in conformance with the pediatric population at higher risk for developing DEC diarrhea.
Databáze: MEDLINE
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