Influence of dietary intakes of erythorbic acid on plasma vitamin C analyses.

Autor: Sauberlich HE; Department of Nutrition Sciences, University of Alabama, Birmingham 35294., Wood SM, Tamura T, Freeberg LE
Jazyk: angličtina
Zdroj: The American journal of clinical nutrition [Am J Clin Nutr] 1991 Dec; Vol. 54 (6 Suppl), pp. 1319S-1322S.
DOI: 10.1093/ajcn/54.6.1319s
Abstrakt: D-Erythorbic acid is an epimer of L-ascorbic acid, but lacks antiscorbutic activity. It is commonly used as a food additive, particularly in processed meat items. Except for high-performance liquid chromatography (HPLC) methodology, the commonly used analytical procedures to measure vitamin C do not distinguish between the two isomers. A study with seven adult women demonstrated that the concentration of erythorbic acid present in food items commonly consumed was sufficient to produce interference in plasma vitamin C analyses. With the meals used, 7-23% of the apparent vitamin C in plasma obtained 2 h after the ingestion of the meals was actually erythorbic acid when analyzed by HPLC. To avoid falsely high plasma-serum vitamin C values as a result of erythorbic acid ingestion, the analyses should be conducted on overnight fasting blood specimens or with the use of an HPLC-amperometric method.
Databáze: MEDLINE