Comparative study of enzyme-linked immunosorbent assay and radioimmunoassay techniques in determining serum placental protein 14 levels in gynecologic patients.

Autor: Scherbakova LA; Department of Biochemistry, Second Medical Institute, Moscow, USSR., Göcze PM, Olefirenko GA, Than GN, Szabò DG, Petrunin DD, Tatarinov YS, Csaba IF
Jazyk: angličtina
Zdroj: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine [Tumour Biol] 1991; Vol. 12 (5), pp. 267-71.
DOI: 10.1159/000217714
Abstrakt: A comparative analysis of radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) techniques in determining placental protein 14 (PP14) levels in gynecologic patients was performed. Serum PP14 levels were assessed in the patients in the last period of gestation, during menopause and in healthy nonpregnant controls. The possible discrepancy in PP14 levels was also examined in gynecologic patients with benign and malignant tumors. Both RIA and ELISA techniques proved to be sufficiently sensitive to measure PP14 concentration.
Databáze: MEDLINE