| Autor: |
Sidorik LL; Institute of Molecular Biology and Genetics, Ukrainian Academy of Sciences, Kiev, USSR., Gudzera OI, Dragovoz VA, Tukalo MA, Beresten SF |
| Jazyk: |
angličtina |
| Zdroj: |
FEBS letters [FEBS Lett] 1991 Nov 04; Vol. 292 (1-2), pp. 76-8. |
| DOI: |
10.1016/0014-5793(91)80838-t |
| Abstrakt: |
Monospecific polyclonal antibodies (pAbs) against highly purified bovine seryl-tRNA synthetase (SerRS, EC 6.1.1.1) were prepared and their specificity tested. The interactions of pAbs with SerRS from different organisms were investigated by protein immunoblotting and ELISA methods. pAbs inhibit eukaryotic SerRS aminoacylating activity and exert no effect on SerRS activity from prokaryotes. It is proposed that prokaryotic and eukaryotic SerRS evolve from different ancestor genes. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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