| Autor: |
Caminha Mde F; Instituto de Medicina Integral Prof. Fernando Figueira, Recife, PE, Brasil. fatimacaminha@imip.org.br, Batista Filho M, Fernandes TF, Arruda IK, Diniz Ada S |
| Jazyk: |
English; Portuguese |
| Zdroj: |
Revista de saude publica [Rev Saude Publica] 2009 Aug; Vol. 43 (4), pp. 699-706. Date of Electronic Publication: 2009 Jun 19. |
| DOI: |
10.1590/s0034-89102009005000038 |
| Abstrakt: |
A systematic review on studies evaluating the effect of applying megadoses of vitamin A on the retinol concentrations in maternal milk and blood, as a short-term measure for preventing hypovitaminosis A, was conducted. Based on the strategy of the Brazilian Cochrane Center for randomized trials, 115 published papers were identified in PubMed. From these, through a set of inclusion/exclusion criteria, 14 articles published between 1993 and 2007 were selected. The effects of interventions with three posological regimens (200,000, 300,000 and 400,000 IU) of vitamin A were analyzed. Out of 11 experiments conducted on maternal milk, nine presented elevation of the retinol levels in comparison with the control group; out of nine that evaluated maternal blood, four showed elevation at varying times after applying megadoses of vitamin A. It was concluded that the results from administration of vitamin A at high doses were positive in 82% of the trials on maternal milk, but less notable in relation to maternal blood. No significant differences regarding the posological regimens applied were observed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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