[Not Available].
Autor: | Simon BI; New Jersey Dental School, USA. simonbi@umdnj.edu, Zatcoff AL, Kong JJ, O'Connell SM |
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Jazyk: | angličtina |
Zdroj: | The open dentistry journal [Open Dent J] 2009 May 20; Vol. 3, pp. 92-9. Date of Electronic Publication: 2009 May 20. |
DOI: | 10.2174/1874210600903010092 |
Abstrakt: | Background: The healing potential of platelet growth factors has generated interest in using Platelet-Rich Plasma (PRP) in ridge preservation procedures. A canine study was performed to determine if extraction sites treated with platelet-rich fibrin matrix (PRFM) exhibit enhanced healing compared to sites treated with non-viable materials. Methods: Four dog's extraction sockets were treated individually with PRFM, PRFM and membrane, Demineralized Freeze-Dried Bone Allograft (DFDBA) and membrane, PRFM and DFDBA, and untreated control. Treatment sequencing permitted clinical and histologic evaluation of healing at 10 days, 2, 3, 6 and 12 weeks. Results: Healing was more rapid in the PRFM and PRFM and membrane sites. By 3 weeks those sockets had osseous fill. Sites containing DFDBA had little new bone at 6 weeks. By 12 weeks those sockets had osseous fill but DFDBA particles were still noted in coronal areas. Conclusions: PRFM alone may be the best graft for ridge preservation procedures. Advantages: faster healing, and elimination of disadvantages involved in using barrier membranes. |
Databáze: | MEDLINE |
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