Clarithromycin susceptibility testing of Mycobacterium avium complex using 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride microplate assay with Middlebrook 7H9 broth.

Autor: Park YK; Korean Institute of Tuberculosis, Seoul, Korea., Koh WJ, Kim SO, Shin S, Kim BJ, Cho SN, Lee SM, Chang CL
Jazyk: angličtina
Zdroj: Journal of Korean medical science [J Korean Med Sci] 2009 Jun; Vol. 24 (3), pp. 511-2. Date of Electronic Publication: 2009 Jun 15.
DOI: 10.3346/jkms.2009.24.3.511
Abstrakt: A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and 5 were resistant according to the new and the standard method. STC counts the low cost and reduces the number of procedures needed for susceptibility testing.
Databáze: MEDLINE