| Autor: |
Noungoue DT; Department of Organic Chemistry, Faculty of Science, TWAS Research Unit (TRU) of University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon. didetchamo@yahoo.fr, Chaabi M, Ngouela S, Antheaume C, Boyom FF, Gut J, Rosenthal PJ, Lobstein A, Tsamo E |
| Jazyk: |
angličtina |
| Zdroj: |
Zeitschrift fur Naturforschung. C, Journal of biosciences [Z Naturforsch C J Biosci] 2009 Mar-Apr; Vol. 64 (3-4), pp. 210-4. |
| DOI: |
10.1515/znc-2009-3-410 |
| Abstrakt: |
A phytochemical study of the stem bark of Vismia laurentii resulted in the isolation of a tetracyclic triterpene, tirucalla-7,24-dien-3-one (1), and seven other known compounds: 3-geranyloxyemodin (2), vismiaquinone A (3), vismiaquinone B (4), bivismiaquinone (5), epifriedelinol (6), betulinic acid (7) and stigmasta-7,22-dien-3-ol (8). The structure of all these compounds was elucidated by spectroscopic means. The stem bark extract and compounds 1 and 3 showed good antimalarial activity against the W2 strain of Plasmodium falciparum. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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