| Autor: |
Tsyb AF; Medical Radiological Research Center, Russian Academy of Medical Sciences, Obninsk, Russia., Yuzhakov VV, Roshal' LM, Sukhikh GT, Konoplyannikov AG, Sushkevich GN, Yakovleva ND, Ingel' IE, Bandurko LN, Sevan'kaeva LE, Mikhina LN, Fomina NK, Marei MV, Semenova ZhB, Konoplyannikova OA, Kal'sina SSh, Lepekhina LA, Semenkova IV, Agaeva EV, Shevchuk AS, Pavlova LN, Tokarev OY, Karaseva OV, Chernyshova TA |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2009 Jan; Vol. 147 (1), pp. 132-46. |
| DOI: |
10.1007/s10517-009-0432-3 |
| Abstrakt: |
We studied the effect of transplantation of human stem cells from various tissues on reparative processes in the brain of rats with closed craniocerebral injury. Combined treatment with standard drugs and systemic administration of xenogeneic stem cells had a neuroprotective effect. The morphology of neurons rapidly returned to normal after administration of fetal neural stem cells. Fetal mesenchymal stem cells produced a prolonged effect on proliferative activity of progenitor cells in the subventricular zone of neurogenesis. Adult mesenchymal stem cells had a strong effect on recovery of the vascular bed in ischemic regions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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