Separation of hydroxyquinolines by high-performance liquid chromatography.

Autor: Nagiel-Ostaszewski I; American Health Foundation, Valhalla, New York 10595-1599., Vavrek MT, Weisburger JH
Jazyk: angličtina
Zdroj: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1991 Jun; Vol. 21 (6), pp. 751-4.
DOI: 10.3109/00498259109039514
Abstrakt: 1. Hydroxyquinolines are important chemicals for pharmaceutical and cosmetic use. This report describes an improved method for separating these chemicals, by utilizing a high-performance liquid chromatography technique. 2. 8-Hydroxyquinoline is an excellent chelating agent. Previous separation procedures failed because of this property. An important requirement for the success of the method described is to provide a metal-free environment for the separation of hydroxyquinolines by replacing metal tubing with Polyplex and polyether-ether ketone (PEEK) tubing and utilizing a metal-free Hamilton PRP-1 column.
Databáze: MEDLINE