| Autor: |
Deutman AB; Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands., Monnereau C, Moalin M, Coumans RG, Veling N, Coenen M, Smits JM, de Gelder R, Elemans JA, Ercolani G, Nolte RJ, Rowan AE |
| Jazyk: |
angličtina |
| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2009 Jun 30; Vol. 106 (26), pp. 10471-6. Date of Electronic Publication: 2009 May 21. |
| DOI: |
10.1073/pnas.0810145106 |
| Abstrakt: |
The cooperative binding effects of viologens and pyridines to a synthetic bivalent porphyrin receptor are used as a model system to study how the magnitudes of these effects relate to the experimentally obtained values. The full thermodynamic and kinetic circles concerning both activation and inhibition of the cage of the receptor for the binding of viologens were measured and evaluated. The results strongly emphasize the apparent character of measured binding and rate constants, in which the fractional saturation of receptors with other guests is linearly expressed in these constants. The presented method can be used as a simple tool to better analyze and comprehend the experimentally observed kinetics and thermodynamics of natural and artificial cooperative systems. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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