| Autor: |
Santos Gorjón P; Servicio de ORL y PCF, Hospital Universitario de Salamanca, Salamanca, Spain. pabmaransantos@hotmail.com, Gómez González JL, Batuecas Caletrío A, Flores Corral MT, Sánchez González F |
| Jazyk: |
Spanish; Castilian |
| Zdroj: |
Acta otorrinolaringologica espanola [Acta Otorrinolaringol Esp] 2009 Mar-Apr; Vol. 60 (2), pp. 141-3. |
| DOI: |
10.1016/s2173-5735(09)70117-6 |
| Abstrakt: |
Desmoplastic small round cell tumour (DSRCT) is a rare disease usually affecting young males. There are no other articles with a sub-maxillary location. The tumour consists of nests and masses of undifferentiated small round cells embedded in a desmoplastic stroma. The co-expression of epithelial, muscular and neuronal antigens distinguishes this entity from other small round cell tumours. The t(11;22)(p13;q12) translocation is a recurrent characteristic of this type of tumour. We report a case of desmoplastic small round cell tumour of the sub-maxillary gland, with an evolution of 8 months, affecting a 36 year old male. He suffered chronic lymphatic leukaemia five years ago and needed a bone marrow transplant. There was a 4x3 cm tumour. There were no signs of malignancy on the CT scan. A right sub-maxillectomy was performed. The pathology analysis gave a diagnosis of DSRCT. Post-surgical radiotherapy was given. The definitive diagnosis was reached using immunohistochemical techniques, such as polyphenotypical differentiation (epithelial, mesenchymal and neural), and by demonstration of translocation (11;22)(p13;q12). Sub-maxillary location is very rare. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
