| Autor: |
Fedoseeva VN, Kamysheva VA, Fedoskova TG, Nekrasova OV |
| Jazyk: |
ruština |
| Zdroj: |
Patologicheskaia fiziologiia i eksperimental'naia terapiia [Patol Fiziol Eksp Ter] 2009 Jan-Mar (1), pp. 13-8. |
| Abstrakt: |
Myofibrillar protein tropomyosin (TM) is a normal physiological protein participating in regulation of muscular contraction. It is widely prevalent among living organisms. This explains cross-reactivity of allergic patients to home dust, sea fish, cockroaches, etc. The presence of similar IgE-binding epitopes in TM of different origin is a key factor in development of cross-reactivity (CR). CR to TM is a general biological phenomenon. We consider modified TM as a basic component in design of allergovaccines of a new generation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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