Ligands, cell-based models, and readouts required for Toll-like receptor action.

Autor: Dellacasagrande J; OPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James' Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.com
Jazyk: angličtina
Zdroj: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2009; Vol. 517, pp. 15-32.
DOI: 10.1007/978-1-59745-541-1_2
Abstrakt: This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.
Databáze: MEDLINE