Hepatitis A seroprevalence and demographics in Turkish children in Ankara.

Autor: Sac RU; Department of Pediatrics, Ankara Training and Research Hospital, Ankara, Turkey. rukiyeunsal@hotmail.com, Bostanci I, Dallar Y, Cihan G, Atli O
Jazyk: angličtina
Zdroj: Pediatrics international : official journal of the Japan Pediatric Society [Pediatr Int] 2009 Feb; Vol. 51 (1), pp. 5-8.
DOI: 10.1111/j.1442-200X.2008.02671.x
Abstrakt: Background: Hepatitis A virus (HAV) is the most common cause of hepatitis in childhood and an important public health problem. The objective of the present study was to determine the seroprevalence of hepatitis A and patient demographics in children between 1 and 15 years old who were admitted to a pediatric outpatient clinic in Ankara, Turkey.
Methods: Hepatitis IgM and G antibodies were determined in the sera of children who attended the outpatient clinic. Informed consent was obtained from all subjects or their parents.
Results: The mean age of the children (n = 335) was 7.9 +/- 2.1 years; 47.5% of them were girls. The overall anti-HAV IgG prevalence in children aged 1-15 years was 47.2%. The positivity of hepatitis A IgM was highest in the 6-10 years age group (22.7%; P < 0.001). HAV IgG was highest in the 11-15 years age group (69.4%; P < 0.001). A total of 95.6% of the children had social insurance, 49.3% were living in poverty. The socioeconomic level of 82.4% of subjects was low. The history of hepatitis in their families was 6.9%.
Conclusions: Hepatitis A is intermediate endemic in Ankara and children must be vaccinated before school age, in addition to health education and improved sanitation.
Databáze: MEDLINE
Externí odkaz: