Four-component reaction for the preparation of alpha-amino phosphonates from methyleneaziridines.

Autor: Mumford PM; Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, United Kingdom., Tarver GJ, Shipman M
Jazyk: angličtina
Zdroj: The Journal of organic chemistry [J Org Chem] 2009 May 01; Vol. 74 (9), pp. 3573-5.
DOI: 10.1021/jo9004958
Abstrakt: Alpha-amino phosphonates can be rapidly assembled in moderate to good yields (42-65%) via a "one-pot" process that brings together four components through the construction of three new intermolecular bonds.
Databáze: MEDLINE