Long-term neurodevelopmental outcome after fetal arrhythmia.

Autor: Lopriore E; Department of Pediatrics, Division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands. e.lopriore@lumc.nl, Aziz MI, Nagel HT, Blom NA, Rozendaal L, Kanhai HH, Vandenbussche FP
Jazyk: angličtina
Zdroj: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2009 Jul; Vol. 201 (1), pp. 46.e1-5. Date of Electronic Publication: 2009 Apr 03.
DOI: 10.1016/j.ajog.2009.02.002
Abstrakt: Objective: The purpose of this study was to determine the long-term neurodevelopmental outcome in fetuses with severe tachy- or bradyarrhythmia.
Study Design: This was a follow-up study to assess the neurologic, mental, and psychomotor development in cases with fetal cardiac arrhythmia.
Results: A total of 44 fetuses were diagnosed with fetal tachy- or bradyarrhythmia: 28 fetuses had supraventricular tachycardia (SVT); 7 fetuses had atrial flutter (AF), and 9 fetuses had atrioventricular block (AVB). The mortality rate was low (6%; 2/35 fetuses) in the SVT and AF groups and high in the AVB group (78%; 7/9 fetuses). Six patients were lost to follow-up evaluation (14%). Neurodevelopmental outcome was normal in all survivors in the SVT and AF groups, except for 1 patient who experienced plexus brachialis injury because of shoulder dystocia. Two of the 3 survivors in the AVB group had severe developmental delay.
Conclusion: The mortality rate and neurodevelopmental impairment in infants with SVT and AF are low, but the mortality rate in infants with AVB is elevated.
Databáze: MEDLINE
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