| Autor: |
Nanda S; Department of Internal Medicine, St. Luke's Hospital, Bethlehem, PA, USA. sudipnanda2000@yahoo.com, Longo S, Bhatt SP, Pamula J, Sharma SG, Dale TH |
| Jazyk: |
angličtina |
| Zdroj: |
Annals of clinical biochemistry [Ann Clin Biochem] 2009 May; Vol. 46 (Pt 3), pp. 257-60. Date of Electronic Publication: 2009 Mar 23. |
| DOI: |
10.1258/acb.2009.008237 |
| Abstrakt: |
We have documented a unique instance of diabetic ketoacidosis (DKA)-induced stress-related cardiomyopathy (CMP) in a 46-yr-old Caucasian female with type I diabetes mellitus. In times of stress, tissues with high capacity for aerobic metabolism, like myocardium, can preferentially change their metabolic substrate to ketones. The myocyte has a decreased ability to metabolize glucose and free fatty acids in stress CMP. To the best of our knowledge this is the first report of stress CMP complicating DKA. A possible mechanism for the same is hypothesized. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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