| Autor: |
Tamer GG Jr; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA. gtamer@purdue.edu, Luh WM, Talavage TM |
| Jazyk: |
angličtina |
| Zdroj: |
IEEE transactions on bio-medical engineering [IEEE Trans Biomed Eng] 2009 Jul; Vol. 56 (7), pp. 1919-28. Date of Electronic Publication: 2009 Mar 16. |
| DOI: |
10.1109/TBME.2009.2016573 |
| Abstrakt: |
Acoustic imaging noise produced during functional magnetic resonance imaging (fMRI) studies can hinder auditory fMRI research analysis by altering the properties of the acquired time-series data. Acoustic imaging noise can be especially confounding when estimating the time course of the hemodynamic response (HDR) in auditory event-related fMRI (fMRI) experiments. This study is motivated by the desire to establish a baseline function that can serve not only as a comparison to other quantities of acoustic imaging noise for determining how detrimental is one's experimental noise, but also as a foundation for a model that compensates for the response to acoustic imaging noise. Therefore, the amplitude and spatial extent of the HDR to the elemental unit of acoustic imaging noise (i.e., a single ping) associated with echoplanar acquisition were characterized and modeled. Results from this fMRI study at 1.5 T indicate that the group-averaged HDR in left and right auditory cortex to acoustic imaging noise (duration of 46 ms) has an estimated peak magnitude of 0.29% (right) to 0.48% (left) signal change from baseline, peaks between 3 and 5 s after stimulus presentation, and returns to baseline and remains within the noise range approximately 8 s after stimulus presentation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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