| Autor: |
De Oliveira Silva FR; Universidade Federal de São Paulo UNIFESP, Departamento de Medicina, Disciplina de Nefrologia, São Paulo, Brazil., Monteiro AM, Neto AM, Gidlund M, Junior ND, Courrol LC |
| Jazyk: |
angličtina |
| Zdroj: |
Luminescence : the journal of biological and chemical luminescence [Luminescence] 2009 May-Jun; Vol. 24 (3), pp. 189-93. |
| DOI: |
10.1002/bio.1094 |
| Abstrakt: |
Low-density lipoprotein (LDL) is known as 'bad' cholesterol. If too much LDL circulates in the blood it can be retained in the walls of the arteries, causing atherosclerosis. In this paper we showed an alternative method to quantify LDL using the europium tetracycline (EuTc) indicator. The optical properties of the EuTc complex were investigated in aqueous solutions containing LDL. An enhancement was observed of the europium luminescence in the solutions with LDL compared those without the lipoprotein. A method to quantify the amount of LDL in a sample, based on EuTc enhanced luminescence, is proposed. The enhancement mechanism is also discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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