[The use of statins, a new approach to the treatment of autoimmune diseases].
Autor: | Shirinskiĭ IV, Kozlov VA, Shirinskiĭ VS |
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Jazyk: | ruština |
Zdroj: | Vestnik Rossiiskoi akademii meditsinskikh nauk [Vestn Ross Akad Med Nauk] 2009 (2), pp. 26-32. |
Abstrakt: | HMG-CoA inhibitors (statins) are widely used for the prevention of cardiovascular events and the management of hypercholesterolemia. Recently, multiple cholesterol-independent properties of statins have been discovered. The present review focuses on immunomodulatory and anti-inflammatory effects of statins and their implications for the treatment of autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. |
Databáze: | MEDLINE |
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