[The use of statins, a new approach to the treatment of autoimmune diseases].

Autor: Shirinskiĭ IV, Kozlov VA, Shirinskiĭ VS
Jazyk: ruština
Zdroj: Vestnik Rossiiskoi akademii meditsinskikh nauk [Vestn Ross Akad Med Nauk] 2009 (2), pp. 26-32.
Abstrakt: HMG-CoA inhibitors (statins) are widely used for the prevention of cardiovascular events and the management of hypercholesterolemia. Recently, multiple cholesterol-independent properties of statins have been discovered. The present review focuses on immunomodulatory and anti-inflammatory effects of statins and their implications for the treatment of autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, and psoriasis.
Databáze: MEDLINE