[Fluoroquinolones: antimicrobial activity and chemotherapeutic efficacy with respect to various pathogens in highly dangerous diseases].

Autor: Bondareva TA, Kalininskiĭ VB, Borisevich IV, Bondarev VP, Kozhukhov VV, Amosov MIu, Baramzina GV, Fomenkov OO, Krinitsyn FV
Jazyk: ruština
Zdroj: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] [Antibiot Khimioter] 2007; Vol. 52 (11-12), pp. 21-4.
Abstrakt: Comparative in vitro and in vivo efficacy of new fluoroquinolones with respect to pathogens of tularemia, glanders, melioidosis and anthrax was estimated. It was shown that the strains of the tularemia, glanders, melioidosis and anthrax pathogens were in vitro highly susceptible to the new agents. The experiments on laboratory animals demonstrated that pefloxacin and sparfloxacin had extremely broad spectra and were of special value in emergency prophylaxis of tularemia, glanders, melioidosis and anthrax.
Databáze: MEDLINE