Lobular carcinoma in situ: mammographic-pathologic correlation of results of needle-directed biopsy.

Autor: Sonnenfeld MR; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115., Frenna TH, Weidner N, Meyer JE
Jazyk: angličtina
Zdroj: Radiology [Radiology] 1991 Nov; Vol. 181 (2), pp. 363-7.
DOI: 10.1148/radiology.181.2.1924773
Abstrakt: The mammographic and histologic findings were reviewed in 41 consecutive cases of isolated lobular carcinoma in situ (LCIS) unassociated with any malignant diagnosis. Thirty-one needle-directed breast biopsies were performed to evaluate clustered microcalcifications. In 24 of the 31 cases, the calcifications were found in areas of benign breast disease, with LCIS representing a separate process. In the few cases in which microcalcifications were seen in association with LCIS, a greater number of similar calcifications were present in adjacent benign disease. Soft-tissue abnormalities necessitating the performance of a biopsy represented benign foci, except in one patient with LCIS in and adjacent to a fibroadenoma. The authors conclude that LCIS has no characteristic mammographic features. LCIS is detected as an incidental finding at breast biopsy, with the mammographic abnormality predominantly reflecting a benign process.
Databáze: MEDLINE