Cisplatinum and docetaxel for ovarian cancer in pregnancy.

Autor: Rouzi AA; Department of Obstetrics and Gynecology, King Abdulaziz University, PO Box 80215, Jeddah 21589, Saudi Arabia. aarouzi@gmail.com, Sahly NN, Sahly NF, Alahwal MS
Jazyk: angličtina
Zdroj: Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2009 Nov; Vol. 280 (5), pp. 823-5. Date of Electronic Publication: 2009 Feb 26.
DOI: 10.1007/s00404-009-0992-5
Abstrakt: Background: There is limited data on chemotherapy for advanced ovarian cancer during pregnancy. Most women received cisplatin-based chemotherapy. There are no published reports on the use of docetaxel for ovarian cancer in pregnancy.
Case: A 32-year-old pregnant lady underwent laparatomy at 18-week gestation for ruptured ovarian cyst. The pregnancy was the result of in vitro fertilization with intracytoplasmic sperm injection. Left salpingo-oophorectomy and omental biopsy were done. A diagnosis of stage IIIC, poorly differentiated papillary serous adenocarcinoma of the ovary was made. She was given four cycles of cisplatinum and docetaxel followed by cesarean hysterectomy, right salpingo-oophorectomy, and cytoreductive surgery. The mother is well and has completed six cycle of chemotherapy.
Conclusion: This is the first report on the use of docetaxel during pregnancy for ovarian cancer.
Databáze: MEDLINE
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