| Autor: |
Sagara Y; Dept. of Breast-Surgical Oncology and Radiology, Sagara Hospital., Rai Y, Sagara Y, Matsuyama Y, Baba S, Tamada S, Sagara Y, Ando M |
| Jazyk: |
japonština |
| Zdroj: |
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2009 Feb; Vol. 36 (2), pp. 247-50. |
| Abstrakt: |
A paclitaxel injection NK (NK) is a generic product containing the same amount of ingredient as a Taxol Injection. We examined the pharmacokinetics and safety of NK compared to the original product in breast cancer patients. As a result, the transition of plasma paclitaxel concentration and pharmacokinetic parameter in NK and the original drug were almost equal, which suggested that these products were bioequivalent. In adjuvant therapy, there was no significant difference in adverse events reported, and these products were approximately equally safe. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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